DMAP1 抗体 (AA 54-401) (Fluoro488)
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Quick Overview for DMAP1 抗体 (AA 54-401) (Fluoro488) (ABIN7985909)
抗原
See all DMAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 54-401
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原理
- Anti-DMAP1 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DMAP1 recombinant protein (Position: H54-A401).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
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别名
- DMAP1
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背景
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Background: DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene. This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting ly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Gene Full Name: DNA methyltransferase 1 associated protein 1
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基因ID
- 55929
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UniProt
- Q9NPF5
抗原
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