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DISC1 抗体 (N-Term) (HRP)

The HRP-conjugated 兔 多克隆 anti-DISC1 antibody (ABIN7985747) specifically detects DISC1 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7985747
发货至: 中国
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Quick Overview for DISC1 抗体 (N-Term) (HRP) (ABIN7985747)

抗原

See all DISC1 抗体
DISC1 (Disrupted in Schizophrenia 1 (DISC1))

适用

  • 103
  • 45
  • 36
  • 1

宿主

  • 104
  • 5
  • 1

克隆类型

  • 94
  • 18
多克隆

标记

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  • 7
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
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This DISC1 antibody is conjugated to HRP

应用范围

  • 59
  • 37
  • 33
  • 28
  • 20
  • 18
  • 17
  • 14
  • 14
  • 11
  • 4
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 16
    • 15
    • 12
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-DISC1 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human DISC1.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    DISC1 (Disrupted in Schizophrenia 1 (DISC1))

    别名

    DISC1

    背景

    Background: DISC1 (Disrupted in Schizophrenia 1), is a protein that is encoded by the DISC1 gene in humans. Ma et al. (2002) determined that the mouse Disc1 gene maps to chromosome 8 in a region with homology of synteny to human chromosome 1q42. Ozeki et al. (2003) demonstrated that rodent Disc1 expression displayed pronounced developmental regulation, with the highest levels in late embryonic life during development of the cerebral cortex. Millar et al. (2005) showed that DISC1 interacts with the UCR2 domain of phosphodiesterase-4B, implicated in susceptibility to schizophrenia, and that elevation of cellular cAMP leads to dissociation of PDE4B from DISC1 and in increase in PDE4B activity.

    Gene Full Name: DISC1 scaffold protein

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

    基因ID

    27185

    UniProt

    Q9NRI5

    途径

    Regulation of Cell Size
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