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DLG4 抗体 (AA 18-711) (Fluoro550)

The 兔 多克隆 anti-DLG4 antibody is suitable to detect DLG4 in samples from 大鼠, 人 和 小鼠. It has been validated for FACS.
产品编号 ABIN7985665
发货至: 中国
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Quick Overview for DLG4 抗体 (AA 18-711) (Fluoro550) (ABIN7985665)

抗原

See all DLG4 抗体
DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

适用

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大鼠, 人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This DLG4 antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
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    AA 18-711

    原理

    Anti-PSD95/DLG4 Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PSD95/DLG4 recombinant protein (Position: D18-L711).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

    别名

    DLG4

    背景

    Background: DLG4 discs large homolog 4, also known as PSD95 or SAP-90, is a protein that in humans is encoded by the DLG4 gene. It is a member of the membrane-associated guanylate kinase (MAGUK) family. This gene is mapped to 17p13.1. DLG4 can heteromultimerize with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synapses. DLG4 can orchestrate synaptic development and it has a role in synapse stabilization and plasticity. Ubiquitination of DLG4 through an MDM2-mediated pathway can regulate AMPA receptor surface expression during synaptic plasticity.

    Gene Full Name: discs large MAGUK scaffold protein 4

    基因ID

    1742

    UniProt

    P78352

    途径

    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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