Desmoglein 3 抗体 (AA 384-957) (APC)
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北京 101111
Quick Overview for Desmoglein 3 抗体 (AA 384-957) (APC) (ABIN7985017)
抗原
See all Desmoglein 3 (DSG3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 384-957
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原理
- Anti-Desmoglein 3/PVA/DSG3 Antibody APC Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Desmoglein 3/PVA/DSG3 recombinant protein (Position: R384-Q957).
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亚型
- IgG
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 IHC 宿主: 小鼠 Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 IHC 宿主: 小鼠 Monoclonal 543M unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 IHC, ICC 宿主: 小鼠 Monoclonal BC11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Desmoglein 3 (DSG3)
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别名
- DSG3
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背景
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Background: Desmoglein3 is also known as PVA(Pemphigus Vulgaris Antigen). Pemphigus vulgaris(PV) and pemphigus foliaceus(PF) are autoimmune diseases of the skin which have as target antigens 2 different members of the desmoglein subfamily of the desmosomal cadherins: pemphigus vulgaris antigen(PVA, or desmoglein-3) in the case of PV and desmoglein I in the case of PF. The DSG3 gene, like the genes for DSG1 and DSG2, is located on chromosome 18. The human DSG3 gene consists of 15 exons and spans more than 23 kb. DSG3 and DSG1 are the autoantigens of pemphigus vulgaris and pemphigus foliaceus, respectively. DSG3 and DSG1 are the target antigens in PNP, and IgG autoantibodies against DSG3 in PNP sera play a pathogenic role in the loss of keratinocyte adhesion and blistering.
Gene Full Name: desmoglein 3
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基因ID
- 1830
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UniProt
- P32926
抗原
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