Desmocollin 3 抗体 (AA 87-676)
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北京 101111
Quick Overview for Desmocollin 3 抗体 (AA 87-676) (ABIN7984965)
抗原
See all Desmocollin 3 (DSC3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 87-676
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原理
- Anti-DSC3 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-DSC3 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DSC3 recombinant protein (Position: L87-Q676).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Rat ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- Desmocollin 3 (DSC3)
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别名
- DSC3
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背景
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Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.
Gene Full Name: desmocollin 3
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分子量
- 90-110 kDa
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基因ID
- 1825
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UniProt
- Q14574
抗原
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