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Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体 (Fluoro647)

This 兔 多克隆 antibody specifically detects Deoxyuridine Triphosphatase in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7984896
发货至: 中国
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Quick Overview for Deoxyuridine Triphosphatase (DUT) (C-Term) 抗体 (Fluoro647) (ABIN7984896)

抗原

See all Deoxyuridine Triphosphatase (DUT) 抗体
Deoxyuridine Triphosphatase (DUT)

适用

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宿主

  • 102
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克隆类型

  • 92
  • 13
多克隆

标记

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Fluoro647

应用范围

  • 80
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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-DUT Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human DUT, different from the related rat and mouse sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Deoxyuridine Triphosphatase (DUT)

    别名

    DUT

    背景

    Background: Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low intracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. dUTPase activity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and dUTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the cytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35 % identity with the E.coli dUTPase and 53 % identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial forms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the use of alternative 5-prime exons. Human dUTPase exhibits 92 % identity with rat. Moreover, this enzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis.

    Gene Full Name: deoxyuridine triphosphatase

    Sequence Similarities: Belongs to the dUTPase family.

    基因ID

    1854

    UniProt

    P33316
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