Deoxyguanosine Kinase 抗体 (AA 76-277) (Fluoro550)
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Quick Overview for Deoxyguanosine Kinase 抗体 (AA 76-277) (Fluoro550) (ABIN7984857)
抗原
See all Deoxyguanosine Kinase (DGUOK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 76-277
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原理
- Anti-DGUOK Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DGUOK recombinant protein (Position: Q76-L277).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Deoxyguanosine Kinase (DGUOK)
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别名
- DGUOK
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背景
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Background: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Gene Full Name: deoxyguanosine kinase
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基因ID
- 1716
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UniProt
- Q16854
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途径
- Ribonucleoside Biosynthetic Process
抗原
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