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DOCK2 抗体 (AA 560-1809) (Fluoro550)

The 兔 多克隆 anti-DOCK2 antibody is suitable to detect DOCK2 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7984585
发货至: 中国
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Quick Overview for DOCK2 抗体 (AA 560-1809) (Fluoro550) (ABIN7984585)

抗原

See all DOCK2 抗体
DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

适用

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人, 小鼠, 大鼠

宿主

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  • 2

克隆类型

  • 45
  • 13
多克隆

标记

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This DOCK2 antibody is conjugated to Fluoro550

应用范围

  • 47
  • 17
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  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 11
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    • 2
    • 1
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    AA 560-1809

    原理

    Anti-DOCK2 Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DOCK2 recombinant protein (Position: E560-T1809).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

    别名

    DOCK2

    背景

    Background: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. Mutations in this gene result in immunodeficiency 40 (IMD40), a combined form of immunodeficiency that affects T cell number and function, also with variable defects in B cell and NK cell function.

    Gene Full Name: dedicator of cytokinesis 2

    基因ID

    1794

    UniProt

    Q92608
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