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DDX3X 抗体 (N-Term) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-DDX3X antibody (ABIN7984103) specifically detects DDX3X in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7984103
发货至: 中国
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Quick Overview for DDX3X 抗体 (N-Term) (Fluoro550) (ABIN7984103)

抗原

See all DDX3X 抗体
DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

适用

  • 133
  • 69
  • 59
  • 16
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  • 1
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人, 小鼠, 大鼠

宿主

  • 120
  • 13

克隆类型

  • 118
  • 14
多克隆

标记

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  • 2
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  • 2
  • 1
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This DDX3X antibody is conjugated to Fluoro550

应用范围

  • 85
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  • 6
  • 3
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Flow Cytometry (FACS)
  • 抗原表位

    • 30
    • 18
    • 15
    • 7
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    • 3
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-DDX3/DDX3X Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse sequence.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human DDX3, identical to the related mouse sequence.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

    别名

    DDX3X

    背景

    Background: ATP-dependent RNA helicase DDX3X is an enzyme that in humans is encoded by the DDX3X gene. The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome.

    Gene Full Name: DEAD-box helicase 3 X-linked

    基因ID

    1654

    UniProt

    O00571

    途径

    Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly
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