CYR61 抗体 (AA 54-381)
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北京 101111
Quick Overview for CYR61 抗体 (AA 54-381) (ABIN7982769)
抗原
See all CYR61 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 54-381
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原理
- Anti-CCN1/CYR61 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human CCN1 shares 91.8%,92.1% amino acid (aa) sequence identity with mouse,rat CCN1,respectively.
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产品特性
- Anti-CCN1/CYR61 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively.
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亚型
- IgG
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anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 176-379) antibody
CYR61 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 178-381) antibodyCYR61 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 251-379) antibodyCYR61 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) antibodyCYR61 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (Center) antibodyCYR61 适用: 人, 大鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 54-381) antibodyCYR61 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) antibodyCYR61 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 143-174) antibodyCYR61 适用: 人 WB 宿主: 兔 Polyclonal RB53929 unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 25-381) antibodyCYR61 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) (AA 47-332) antibodyCYR61 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
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别名
- CYR61
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背景
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Background: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.
Gene Full Name: cellular communication network factor 1
Sequence Similarities: Belongs to the CCN family.
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分子量
- 42 kDa
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基因ID
- 3491
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UniProt
- O00622
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途径
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
抗原
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