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CSTB 抗体 (AA 1-98) (Fluoro550)

This 兔 多克隆 antibody specifically detects CSTB in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7982685
发货至: 中国
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Room 801-803
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Quick Overview for CSTB 抗体 (AA 1-98) (Fluoro550) (ABIN7982685)

抗原

See all CSTB 抗体
CSTB (Cystatin B (Stefin B) (CSTB))

适用

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宿主

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克隆类型

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  • 55
多克隆

标记

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This CSTB antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-98

    原理

    Anti-Stefin B/CSTB Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    coli-derived human Stefin B recombinant protein (Position: M1-F98). Human Stefin B shares 78.6 % amino acid (aa) sequence identity with both mouse,rat Stefin B.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Stefin B recombinant protein (Position: M1-F98). Human Stefin B shares 78.6 % amino acid (aa) sequence identity with both mouse and rat Stefin B.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CSTB (Cystatin B (Stefin B) (CSTB))

    别名

    CSTB

    背景

    Background: Cystatin B (CSTB), also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is thought to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.

    Gene Full Name: cystatin B

    Sequence Similarities: Belongs to the cystatin family.

    基因ID

    1476

    UniProt

    P04080

    途径

    Response to Water Deprivation
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