CBS 抗体 (AA 102-342) (Cy3)
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北京 101111
Quick Overview for CBS 抗体 (AA 102-342) (Cy3) (ABIN7982650)
抗原
See all CBS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 102-342
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原理
- Anti-CBS Antibody (monoclonal, 5B5D7) Cy3 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CBS recombinant protein (Position: K102-E342).
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亚型
- IgG1
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CBS (Cystathionine-beta-Synthase (CBS))
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别名
- CBS
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背景
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Background: CBS, Cystathionine Beta-Synthase, catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity. The CBS gene, which is mapped to chromosome 21q22, contains 23 exons, ranging in size from 42 to 299 bp. The human CBS protein can substitute for the endogenous yeast CBS protein in Saccharomyces cerevisiae. The catalytic domain of the CBS protein is located in the N-terminal 409 amino acids, and a regulatory domain is located in the C-terminal 142 amino acids.A mutation that deletes the C-terminal 145 amino acids of CBS could restore activity of several CBS mutant alleles found in homocystinurics.
Gene Full Name: cystathionine beta-synthase like
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基因ID
- 875
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UniProt
- P35520
抗原
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