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CBS 抗体 (AA 331-551) (Fluoro647)

This 兔 多克隆 antibody specifically detects CBS in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7982625
发货至: 中国
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Quick Overview for CBS 抗体 (AA 331-551) (Fluoro647) (ABIN7982625)

抗原

See all CBS 抗体
CBS (Cystathionine-beta-Synthase (CBS))

适用

  • 119
  • 95
  • 62
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 108
  • 35

克隆类型

  • 91
  • 52
多克隆

标记

  • 60
  • 11
  • 10
  • 8
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CBS antibody is conjugated to Fluoro647

应用范围

  • 93
  • 46
  • 43
  • 43
  • 31
  • 17
  • 17
  • 14
  • 13
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 39
    • 15
    • 11
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-551

    原理

    Anti-Cystathionine beta-synthase CBS Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human CBS shares 83% amino acid (aa) sequence identity with both mouse,rat CBS.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CBS recombinant protein (Position: A331-K551). Human CBS shares 83% amino acid (aa) sequence identity with both mouse and rat CBS.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CBS (Cystathionine-beta-Synthase (CBS))

    别名

    CBS

    背景

    Background: Cystathionine-β-synthase, also known as CBS, is an enzyme that in humans is encoded by the CBS gene. It is mapped to 21q22.3 and contains 23 exons, ranging in size from 42 to 299 bp. CBS catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine. It uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.

    Gene Full Name: cystathionine beta-synthase like

    Sequence Similarities: Belongs to the cysteine synthase/cystathionine beta- synthase family.

    基因ID

    875

    UniProt

    P35520
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