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CDK5 抗体 (C-Term) (HRP)

The 兔 多克隆 anti-CDK5 antibody is suitable to detect CDK5 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN7982380
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDK5 抗体 (C-Term) (HRP) (ABIN7982380)

抗原

See all CDK5 抗体
CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CDK5 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    原理

    Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequence.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk5, identical to the related rat and mouse sequence.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

    别名

    CDK5

    背景

    Background: CDK5, Cyclin-Dependent Kinase5, is also know as PSSALRE. The p34 (CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.

    Gene Full Name: cyclin dependent kinase 5

    Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

    基因ID

    1020

    UniProt

    Q00535

    途径

    Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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