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Cyclin B1 抗体 (AA 1-433) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-Cyclin B1 antibody (ABIN7982123) specifically detects Cyclin B1 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7982123
发货至: 中国
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Quick Overview for Cyclin B1 抗体 (AA 1-433) (Fluoro488) (ABIN7982123)

抗原

See all Cyclin B1 (CCNB1) 抗体
Cyclin B1 (CCNB1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cyclin B1 antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
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    AA 1-433

    原理

    Anti-Cyclin B1/CCNB1 Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Cyclin B1 shares 86%,85% amino acid (aa) sequences identity with mouse,rat Cyclin B1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cyclin B1 recombinant protein (Position: M1-V433). Human Cyclin B1 shares 86% and 85% amino acid (aa) sequences identity with mouse and rat Cyclin B1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cyclin B1 (CCNB1)

    别名

    CCNB

    背景

    Background: CCNB also known as Cyclin B1, is a protein that in humans is encoded by the CCNB1 gene, and it is mapped to 5q13.2. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. CCNB contributes to the switch-like all or none behavior of the cell in deciding to commit to mitosis. Its activation is well-regulated, and positive feedback loops ensure that once the cyclin B1-Cdk1 complex is activated, it is not deactivated.

    Gene Full Name: cyclin B1

    Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.

    基因ID

    891

    UniProt

    P14635

    途径

    Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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