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Cullin 4A 抗体 (AA 494-759) (Fluoro647)

The 兔 多克隆 anti-Cullin 4A antibody is suitable to detect Cullin 4A in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7982041
发货至: 中国
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Quick Overview for Cullin 4A 抗体 (AA 494-759) (Fluoro647) (ABIN7982041)

抗原

See all Cullin 4A (CUL4A) 抗体
Cullin 4A (CUL4A)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Cullin 4A antibody is conjugated to Fluoro647

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 494-759

    原理

    Anti-Cullin 4a/CUL4A Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Cullin 4a recombinant protein (Position: M494-A759).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cullin 4A (CUL4A)

    别名

    CUL4A

    背景

    Background: Cullin-4A is a protein that in humans is encoded by the CUL4A gene. It belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. As a result, CUL4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. Interestingly, a component of a CUL4A complex, Cereblon, was discovered to be a major target of the teratogenic agent thalidomide.

    Gene Full Name: cullin 4A

    基因ID

    8451

    UniProt

    Q13619
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