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Cullin 3 抗体 (Middle Region) (PE)

The 兔 多克隆 anti-Cullin 3 antibody is suitable to detect Cullin 3 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7982029
发货至: 中国
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Quick Overview for Cullin 3 抗体 (Middle Region) (PE) (ABIN7982029)

抗原

See all Cullin 3 (CUL3) 抗体
Cullin 3 (CUL3)

适用

  • 75
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人, 小鼠, 大鼠

宿主

  • 73
  • 1
  • 1

克隆类型

  • 59
  • 16
多克隆

标记

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  • 4
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This Cullin 3 antibody is conjugated to PE

应用范围

  • 41
  • 19
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  • 15
  • 13
  • 13
  • 7
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  • 3
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
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    Middle Region

    原理

    Anti-Cullin 3/CUL3 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Cullin 3, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cullin 3 (CUL3)

    别名

    CUL3

    背景

    Background: Cullin-3 (Cul 3), is a protein that in humans is encoded by the CUL3 gene. Kipreos et al. (1996) identified a conserved gene family, designated cullins, with at least 5 members in nematodes, 6 in humans, and 3 in S. cerevisiae. Human CUL3 is an ortholog of nematode cul3. Hartz (2012) mapped the CUL3 gene to chromosome 2q36.2 based on an alignment of the CUL3 sequence with the genomic sequence (GRCh37). Sumara et al. (2007) found that KLHL9, KLHL13, and CUL3 interacted ly in a 370-kD protein complex in HeLa cell lysates. Rondou et al. (2008) showed that interaction between KLHL12 and the CUL3 ubiquitin ligase complex ed ubiquitination of dopamine receptor D4 (DRD4). KLHL12 interacted ly with CUL3 and with the polymorphic intracellular loop-3 of D4. By immunoprecipitation analysis of HeLa cells and HCT116 human colon carcinoma cells expressing epitope-tagged proteins, Kigoshi et al. (2011) showed that KLHL7 interacted with CUL3 and ROC1 (RBX1).

    Gene Full Name: cullin 3

    Sequence Similarities: Belongs to the cullin family.

    基因ID

    8452

    UniProt

    Q13618

    途径

    M Phase
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