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CDCP1 抗体 (AA 74-580) (Fluoro488)

The 兔 多克隆 anti-CDCP1 antibody is suitable to detect CDCP1 in samples from 人. It has been validated for FACS.
产品编号 ABIN7981957
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDCP1 抗体 (AA 74-580) (Fluoro488) (ABIN7981957)

抗原

See all CDCP1 抗体
CDCP1 (CUB Domain Containing Protein 1 (CDCP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDCP1 antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 74-580

    原理

    Anti-CDCP1 Antibody Fluoro488 Conjugated

    预测反应

    Human CDCP1 shares 85.8% amino acid (aa) sequence identity with mouse CDCP1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CDCP1 recombinant protein (Position: E74-V580). Human CDCP1 shares 85.8% amino acid (aa) sequence identity with mouse CDCP1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CDCP1 (CUB Domain Containing Protein 1 (CDCP1))

    别名

    CDCP1

    背景

    Background: CUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). CDCP1/Trask is a 140 kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD) containing five tyrosines. The tyrosine phosphorylation of Trask is tightly regulated and reciprocally linked with the state of cell adhesion. The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsin or EDTA, or seen spontaneously during mitotic detachment. The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype. CDCP1 is widely expressed in human epithelial tissues, but its phosphorylation is only seen in mitotically detached or shedding cells, consistent with its role in the negative regulation of cell adhesion.

    Gene Full Name: CUB domain containing protein 1

    基因ID

    64866

    UniProt

    Q9H5V8
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