CDCP1 抗体 (AA 74-580) (Biotin)
Our Local Distributor
北京 101111
Quick Overview for CDCP1 抗体 (AA 74-580) (Biotin) (ABIN7981955)
抗原
See all CDCP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 74-580
-
原理
- Anti-CDCP1 Antibody Biotin Conjugated
-
预测反应
- Human CDCP1 shares 85.8% amino acid (aa) sequence identity with mouse CDCP1.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human CDCP1 recombinant protein (Position: E74-V580). Human CDCP1 shares 85.8% amino acid (aa) sequence identity with mouse CDCP1.
-
亚型
- IgG
-
-
anti-CUB Domain Containing Protein 1 (CDCP1) (AA 689-836) antibody
CDCP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) (AA 692-836) antibodyCDCP1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 5G3H11 unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) antibodyCDCP1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) (Internal Region) antibodyCDCP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) (AA 582-667) antibodyCDCP1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) antibodyCDCP1 适用: 人, 小鼠, 猴, 犬 WB, FACS 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) (N-Term) antibodyCDCP1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) antibodyCDCP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) (C-Term) antibodyVerified CDCP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CUB Domain Containing Protein 1 (CDCP1) (Extracellular Domain) antibodyCDCP1 适用: 人, 猴, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
-
别名
- CDCP1
-
背景
-
Background: CUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). CDCP1/Trask is a 140 kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD) containing five tyrosines. The tyrosine phosphorylation of Trask is tightly regulated and reciprocally linked with the state of cell adhesion. The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsin or EDTA, or seen spontaneously during mitotic detachment. The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype. CDCP1 is widely expressed in human epithelial tissues, but its phosphorylation is only seen in mitotically detached or shedding cells, consistent with its role in the negative regulation of cell adhesion.
Gene Full Name: CUB domain containing protein 1
-
基因ID
- 64866
-
UniProt
- Q9H5V8
抗原
-
