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CRYAB 抗体 (AA 30-151) (Fluoro594)

The Fluoro594-conjugated 兔 多克隆 anti-CRYAB antibody (ABIN7981925) specifically detects CRYAB in FACS. The antibody is reactive with 人, 大鼠, 小鼠 和 猴 samples.
产品编号 ABIN7981925
发货至: 中国
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Quick Overview for CRYAB 抗体 (AA 30-151) (Fluoro594) (ABIN7981925)

抗原

See all CRYAB 抗体
CRYAB (Crystallin, alpha B (CRYAB))

适用

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人, 大鼠, 小鼠, 猴

宿主

  • 170
  • 87
  • 2

克隆类型

  • 149
  • 110
多克隆

标记

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This CRYAB antibody is conjugated to Fluoro594

应用范围

  • 193
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  • 30
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Flow Cytometry (FACS)
  • 抗原表位

    • 36
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    AA 30-151

    原理

    Anti-Alpha B Crystallin/CRYAB Antibody Fluoro594 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Alpha B Crystallin/CRYAB recombinant protein (Position: E30-Q151).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CRYAB (Crystallin, alpha B (CRYAB))

    别名

    CRYAB

    背景

    Background: Alpha-crystallin B chain is a protein that in humans is encoded by the CRYAB gene. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative splicing results in multiple transcript variants.

    Gene Full Name: crystallin alpha B

    基因ID

    1410

    UniProt

    P02511
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