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CRTC2 抗体 (C-Term) (Biotin)

The 兔 多克隆 anti-CRTC2 antibody is suitable to detect CRTC2 in samples from 人. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN7981822
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CRTC2 抗体 (C-Term) (Biotin) (ABIN7981822)

抗原

See all CRTC2 抗体
CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

适用

  • 107
  • 34
  • 28
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 99
  • 6
  • 4
  • 1

克隆类型

  • 81
  • 29
多克隆

标记

  • 37
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
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  • 2
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  • 1
  • 1
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This CRTC2 antibody is conjugated to Biotin

应用范围

  • 80
  • 36
  • 36
  • 34
  • 7
  • 6
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 17
    • 13
    • 13
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    C-Term

    原理

    Anti-TORC2/CRTC2 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat sequence by three amino acids,and from the related mouse sequence by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human TORC2, different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

    别名

    CRTC2

    背景

    Background: CREB regulated transcription coactivator 2, also known as CRTC2, is a protein which in humans is encoded by the CRTC2 gene. This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.

    Gene Full Name: CREB regulated transcription coactivator 2

    Sequence Similarities: Belongs to the TORC family.

    基因ID

    200186

    UniProt

    Q53ET0

    途径

    AMPK Signaling, Carbohydrate Homeostasis
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