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CRTC2 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects CRTC2 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7981821
发货至: 中国
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Quick Overview for CRTC2 抗体 (N-Term) (ABIN7981821)

抗原

See all CRTC2 抗体
CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

适用

  • 107
  • 33
  • 27
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 99
  • 6
  • 4
  • 1

克隆类型

  • 81
  • 29
多克隆

标记

  • 36
  • 9
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CRTC2 antibody is un-conjugated

应用范围

  • 80
  • 37
  • 37
  • 34
  • 7
  • 6
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 17
    • 14
    • 12
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-TORC2/CRTC2 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    产品特性

    Anti-TORC2/CRTC2 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human TORC2, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

    别名

    CRTC2

    背景

    Background: CREB regulated transcription coactivator 2, also known as CRTC2, is a protein which in humans is encoded by the CRTC2 gene. This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.

    Gene Full Name: CREB regulated transcription coactivator 2

    分子量

    73 kDa

    基因ID

    200186

    UniProt

    Q53ET0

    途径

    AMPK Signaling, Carbohydrate Homeostasis
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