Coxsackie Adenovirus Receptor 抗体 (AA 35-365) (FITC)
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Quick Overview for Coxsackie Adenovirus Receptor 抗体 (AA 35-365) (FITC) (ABIN7981739)
抗原
See all Coxsackie Adenovirus Receptor (CXADR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-365
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原理
- Anti-CXADR Antibody FITC Conjugated
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预测反应
- Human CXADR shares 91.2%,91.5% amino acid (aa) sequence identity with mouse,rat CXADR,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CXADR recombinant protein (Position: E35-V365). Human CXADR shares 91.2% and 91.5% amino acid (aa) sequence identity with mouse and rat CXADR, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))
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别名
- CXADR
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背景
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Background: CXADR(Coxsackie virus and adenovirus receptor) is a protein that in humans is encoded by the CXADR gene, also known as CAR,CVB3-binding protein, Coxsackievirus B-adenovirus receptor. The CAR cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northern blot analysis, they detected highest expression of 1.4-kb and 6-kb CXADR transcripts in pancreas, brain, heart, small intestine, testis, and prostate, lower expression in liver and lung, and no expression in kidney, placenta, peripheral blood leukocytes, thymus, and spleen. In comparison, mouse Cxadr showed highest expression in liver, and lower levels in kidney, heart, lung, and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins , such as: fibronectin, agrin, laminin-1 and tenascin-R.
Gene Full Name: CXADR cell adhesion molecule
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基因ID
- 1525
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UniProt
- P78310
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途径
- Cell-Cell Junction Organization
抗原
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