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CRH 抗体 (C-Term) (HRP)

The 兔 多克隆 anti-CRH antibody is suitable to detect CRH in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7981729
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CRH 抗体 (C-Term) (HRP) (ABIN7981729)

抗原

See all CRH 抗体
CRH (Corticotropin Releasing Hormone (CRH))

适用

  • 100
  • 59
  • 56
  • 6
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 89
  • 23
  • 2
  • 2

克隆类型

  • 95
  • 21
多克隆

标记

  • 53
  • 14
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  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CRH antibody is conjugated to HRP

应用范围

  • 75
  • 36
  • 28
  • 14
  • 14
  • 13
  • 13
  • 13
  • 9
  • 9
  • 6
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 19
    • 15
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-CRF/CRH Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human CRF/CRH, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CRH (Corticotropin Releasing Hormone (CRH))

    别名

    CRH

    背景

    Background: This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.

    Gene Full Name: corticotropin releasing hormone

    基因ID

    1392

    UniProt

    P06850

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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