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Cofilin 抗体 (C-Term) (Fluoro594)

The 兔 多克隆 anti-Cofilin antibody is suitable to detect Cofilin in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for FACS.
产品编号 ABIN7980856
发货至: 中国
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Quick Overview for Cofilin 抗体 (C-Term) (Fluoro594) (ABIN7980856)

抗原

See all Cofilin (CFL1) 抗体
Cofilin (CFL1) (Cofilin 1 (CFL1))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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  • 39
多克隆

标记

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This Cofilin antibody is conjugated to Fluoro594

应用范围

  • 106
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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Cofilin/CFL1 Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Cofilin, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cofilin (CFL1) (Cofilin 1 (CFL1))

    别名

    CFL1

    背景

    Background: Cofilin, a member of the ADF/cofilin family, is actually a protein with 70 % sequence homology to ADF, making it part of the ADF/cofilin family of small ADP-binding proteins. It is a ubiquitous actin-binding factor required for the reorganization of actin filaments. The protein is known to sever actin filaments by creating more positive ends on filament fragments, it can cause depolymerization at the minus end of filaments, thereby preventing their reassembly. As a long-lasting in vivo effect, cofilin recycles older ADP-F-actin, helping cell to maintain ATP-G-actin pool for sustained motility. pH , phosphorylation and phosphoinositides regulate cofilin's binding and associating activity with actin.

    Gene Full Name: cofilin 1

    Sequence Similarities: Contains 1 HMG box DNA-binding domain.

    基因ID

    1072

    UniProt

    P23528

    途径

    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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