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Factor XI 抗体 (AA 79-155) (HRP)

The 兔 多克隆 anti-Factor XI antibody is suitable to detect Factor XI in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7980814
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Factor XI 抗体 (AA 79-155) (HRP) (ABIN7980814)

抗原

See all Factor XI (F11) 抗体
Factor XI (F11) (Coagulation Factor XI (F11))

适用

  • 62
  • 16
  • 15
  • 1
  • 1
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  • 1
人, 大鼠, 小鼠

宿主

  • 47
  • 11
  • 5
  • 3
  • 2

克隆类型

  • 56
  • 12
多克隆

标记

  • 44
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  • 3
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  • 1
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This Factor XI antibody is conjugated to HRP

应用范围

  • 42
  • 22
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  • 14
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  • 11
  • 5
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  • 4
  • 4
  • 4
  • 3
  • 2
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 79-155

    原理

    Anti-FXI/F11 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FXI/F11 recombinant protein (Position: K79-Q155).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Factor XI (F11) (Coagulation Factor XI (F11))

    别名

    F11

    背景

    Background: Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene. This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

    Gene Full Name: coagulation factor XI

    基因ID

    2160

    UniProt

    P03951
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