Claudin 7 抗体 (AA 92-211) (Fluoro488)
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北京 101111
Quick Overview for Claudin 7 抗体 (AA 92-211) (Fluoro488) (ABIN7980524)
抗原
See all Claudin 7 (CLDN7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 92-211
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原理
- Anti-Claudin 7/CLDN-7 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Claudin 7/CLDN-7 recombinant protein (Position: F92-V211).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Claudin 7 (CLDN7)
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别名
- CLDN7
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背景
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Background: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: claudin 7
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基因ID
- 1366
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UniProt
- O95471
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途径
- Hepatitis C
抗原
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