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Claudin 7 抗体 (C-Term) (HRP)

The 兔 多克隆 anti-Claudin 7 antibody is suitable to detect Claudin 7 in samples from 小鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN7980517
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Claudin 7 抗体 (C-Term) (HRP) (ABIN7980517)

抗原

See all Claudin 7 (CLDN7) 抗体
Claudin 7 (CLDN7)

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Claudin 7 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    C-Term

    原理

    Anti-Claudin 7/CLDN-7 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Claudin 7/CLDN-7, which shares 87% and 100% amino acid (aa) sequence identity with human and rat Claudin 7/CLDN-7, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Claudin 7 (CLDN7)

    别名

    Cldn7

    背景

    Background: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

    Gene Full Name: claudin 7

    基因ID

    53624

    UniProt

    Q9Z261

    途径

    Hepatitis C
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