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Claudin 11 抗体 (C-Term) (Fluoro550)

The 兔 多克隆 anti-Claudin 11 antibody is suitable to detect Claudin 11 in samples from 人. It has been validated for FACS.
产品编号 ABIN7980382
发货至: 中国
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Quick Overview for Claudin 11 抗体 (C-Term) (Fluoro550) (ABIN7980382)

抗原

See all Claudin 11 (CLDN11) 抗体
Claudin 11 (CLDN11)

适用

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宿主

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克隆类型

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多克隆

标记

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This Claudin 11 antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-CLDN11 Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human CLDN11, which shares 85% amino acid (aa) sequence identity with both mouse and rat CLDN11.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Claudin 11 (CLDN11)

    别名

    CLDN11

    背景

    Background: Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Gene Full Name: claudin 11

    基因ID

    5010

    UniProt

    O75508

    途径

    Hepatitis C
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