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Integrin Alpha2b 抗体 (AA 351-450)

This anti-Integrin Alpha2b antibody is a 兔 多克隆 antibody detecting Integrin Alpha2b in FACS, WB, ELISA, IHC (fro), IHC (p), IF (p) 和 IF (cc). Suitable for 人 和 大鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN748358
发货至: 中国

Quick Overview for Integrin Alpha2b 抗体 (AA 351-450) (ABIN748358)

抗原

See all Integrin Alpha2b (CD41) 抗体
Integrin Alpha2b (CD41)

适用

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人, 大鼠

宿主

  • 94
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克隆类型

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  • 1
多克隆

标记

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This Integrin Alpha2b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 15
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    AA 351-450

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Cow,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Sugiyama, Gamage, Zyla, Armstrong, Advani, Advani, Wang, Lee: "Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury." in: Journal of virology, Vol. 90, Issue 4, pp. 1812-23, (2016) (PubMed).

    Araki, Ogawara, Suzuki, Kawai, Watanabe, Ono, Higaki: "Augmented EPR effect by photo-triggered tumor vascular treatment improved therapeutic efficacy of liposomal paclitaxel in mice bearing tumors with low permeable vasculature." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 200, pp. 106-14, (2015) (PubMed).

    Lê, Schneider, Boergeling, Berri, Ducatez, Guerin, Adrian, Errazuriz-Cerda, Frasquilho, Antunes, Lina, Bordet, Jandrot-Perrus, Ludwig, Riteau: "Platelet Activation and Aggregation Promote Lung Inflammation and Influenza Virus Pathogenesis." in: American journal of respiratory and critical care medicine, (2015) (PubMed).

    Mei, Yin, Jin, He, Yin: "The regulatory role of the adrenergic agonists phenylephrine and isoproterenol on fetal hemoglobin expression and erythroid differentiation." in: Endocrinology, Vol. 154, Issue 12, pp. 4640-9, (2013) (PubMed).

  • 抗原

    Integrin Alpha2b (CD41)

    别名

    Integrin alpha 2b/CD41

    背景

    Synonyms: CD41, CD41B, GpIIb, AI172977, alphaIIb, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, Itga2b

    Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

    基因ID

    16399

    UniProt

    Q9QUM0

    途径

    Integrin Complex
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