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CNTF 抗体 (AA 2-198)

The 兔 多克隆 anti-CNTF antibody (ABIN7980257) specifically detects CNTF in WB 和 IHC. The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN7980257
发货至: 中国
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Quick Overview for CNTF 抗体 (AA 2-198) (ABIN7980257)

抗原

See all CNTF 抗体
CNTF (Ciliary Neurotrophic Factor (CNTF))

适用

  • 89
  • 66
  • 39
  • 21
  • 3
  • 1
大鼠, 小鼠

宿主

  • 120
  • 10
  • 3
  • 3
  • 1

克隆类型

  • 128
  • 9
多克隆

标记

  • 54
  • 14
  • 11
  • 9
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CNTF antibody is un-conjugated

应用范围

  • 88
  • 48
  • 41
  • 36
  • 19
  • 18
  • 13
  • 13
  • 9
  • 7
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 32
    • 15
    • 13
    • 12
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-198

    原理

    Anti-CNTF Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Mouse CNTF shares 83%,95% amino acid (aa) sequences identity with human,rat CNTF,respectively.

    产品特性

    Anti-CNTF Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse CNTF recombinant protein (Position: A2-M198). Mouse CNTF shares 83% and 95% amino acid (aa) sequences identity with human and rat CNTF, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CNTF (Ciliary Neurotrophic Factor (CNTF))

    别名

    CNTF

    背景

    Background: Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The mouse CNTF gene is on mouse chromosome 19 and that its expression is unaffected in the mouse neurologic mutant wobbler, a form of spinal muscular atrophy. The CNTF protein is highly conserved in evolution. The protein is a potent survival factor for neurons and oligodendrocytes, and it may be involved in reducing tissue destruction during inflammatory attacks. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.

    Gene Full Name: ciliary neurotrophic factor

    Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

    分子量

    29 kDa

    基因ID

    12803

    UniProt

    P51642

    途径

    JAK/STAT Signaling
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