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CNTF 抗体 (AA 2-200) (APC)

This 兔 多克隆 antibody specifically detects CNTF in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7980243
发货至: 中国
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Quick Overview for CNTF 抗体 (AA 2-200) (APC) (ABIN7980243)

抗原

See all CNTF 抗体
CNTF (Ciliary Neurotrophic Factor (CNTF))

适用

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宿主

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克隆类型

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多克隆

标记

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This CNTF antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 2-200

    原理

    Anti-CNTF Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human CNTF shares 83%,84% amino acid (aa) sequences identity with mouse,rat CNTF,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CNTF recombinant protein (Position: A2-M200). Human CNTF shares 83% and 84% amino acid (aa) sequences identity with mouse and rat CNTF, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CNTF (Ciliary Neurotrophic Factor (CNTF))

    别名

    CNTF

    背景

    Background: Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The CNTF gene is located on chromosome 11, as determined using human-hamster somatic cell hybrids. The CNTF protein is highly conserved in evolution. The amino acid (aa) sequences of rat and rabbit CNTF translated from cDNAs display approx. 85 % homology with the deduced aa sequence encoding human CNTF. CNTF induces weight loss and improves glucose tolerance in humans and rodents. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.

    Gene Full Name: ciliary neurotrophic factor

    Sequence Similarities: Belongs to the CNTF family.

    基因ID

    1270

    UniProt

    P26441

    途径

    JAK/STAT Signaling
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