C6orf150 抗体 (AA 208-522) (Biotin)
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Quick Overview for C6orf150 抗体 (AA 208-522) (Biotin) (ABIN7980125)
抗原
See all C6orf150 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 208-522
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原理
- Anti-CGAS Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CGAS recombinant protein (Position: L208-F522).
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亚型
- IgG
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anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 211-395) antibody
C6orf150 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 350-522) antibodyC6orf150 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 208-522) antibodyC6orf150 适用: 人 WB, IHC, ELISA, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 6 Open Reading Frame 150 (C6orf150) (AA 1-185) antibodyC6orf150 适用: 人 WB 宿主: 小鼠 Monoclonal 7E3 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))
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别名
- CGAS
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背景
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Background: cGAS (cyclic GMP-AMP synthase), also known as MB21D1 (Mab-21 domain containing 1), h-cGAS or C6orf150, is a 522 amino acid cytoplasmic nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. cGAS is suggested to have antiviral activity by acting as a key cytosolic DNA sensor. cGAS binds to cytosolic DNA, which leads to cGAMP synthesis and activation of TMEM173, thereby trigger type-I interferon production. Expressed in monocytic cell line THP1, cGAS exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 6q13.
Gene Full Name: cyclic GMP-AMP synthase
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基因ID
- 115004
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UniProt
- Q8N884
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途径
- Activation of Innate immune Response
抗原
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