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IL-33 抗体 (AA 185-264) (Biotin)

This anti-IL-33 antibody is a 兔 多克隆 antibody detecting IL-33 in ELISA, IHC (p) 和 IHC (fro). Suitable for 小鼠 和 大鼠.
产品编号 ABIN748315
发货至: 中国

Quick Overview for IL-33 抗体 (AA 185-264) (Biotin) (ABIN748315)

抗原

See all IL-33 (IL33) 抗体
IL-33 (IL33) (Interleukin 33 (IL33))

适用

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小鼠, 大鼠

宿主

  • 107
  • 38
  • 4
  • 2
  • 2
  • 1
  • 1

克隆类型

  • 113
  • 42
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
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  • 1
  • 1
This IL-33 antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 18
    • 15
    • 11
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-264

    交叉反应

    小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse IL-33

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    IL-33 (IL33) (Interleukin 33 (IL33))

    别名

    IL-33

    背景

    Synonyms: Il-33, Il1f11, NF-HEV, 9230117N10Rik, Interleukin-33, Il33

    Background: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation.

    基因ID

    77125

    UniProt

    Q8BVZ5

    途径

    Production of Molecular Mediator of Immune Response
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