CXCR6 抗体 (C-Term) (Fluoro647)
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北京 101111
Quick Overview for CXCR6 抗体 (C-Term) (Fluoro647) (ABIN7979430)
抗原
See all CXCR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Bonzo/CXCR6 Antibody Fluoro647 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by three amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Bonzo, different from the related mouse and rat sequences by three amino acids.
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibody
Verified CXCR6 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) antibodyCXCR6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (Cytoplasmic Domain) antibodyCXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 3-31), (N-Term) antibodyCXCR6 适用: 人 WB 宿主: 兔 Polyclonal RB33271 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 319-338) antibodyCXCR6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) antibodyCXCR6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. Kim, C. H., Kunkel, E. J., Boisvert, J., Johnston, B., Campbell, J. J., Genovese, M. C., Greenberg, H. B., Butcher, E. C. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. J. Clin. Invest. 107: 595-601, 2001. 2. Liao, F., Alkhatib, G., Peden, K. W. C., Sharma, G., Berger, E. A., Farber, J. M. STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1. J. Exp. Med. 185: 2015-2023, 1997. 3. Matloubian, M., David, A., Engel, S., Ryan, J. E., Cyster, J. G. A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nature Immun. 1: 298-304, 2000. -
说明
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Applications are recommended based on the unconjugated antibody.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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别名
- CXCR6
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背景
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Background: CXCR6 (Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al. (1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al. (2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al. (2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.
Gene Full Name: C-X-C motif chemokine receptor 6
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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基因ID
- 10663
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UniProt
- O00574
抗原
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