CXCR4 抗体 (AA 20-352)
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北京 101111
Quick Overview for CXCR4 抗体 (AA 20-352) (ABIN7979365)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 20-352
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原理
- Anti-CXCR4 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CXCR4 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CXCR4 recombinant protein (Position: D20-S352).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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别名
- CXCR4
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背景
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Background: CXCR4 (Chemokine,CXC Motif, Receptor 4), also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. It is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is also a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1. It functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. It was concluded that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization.
Gene Full Name: C-X-C motif chemokine receptor 4
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分子量
- 40-50 kDa
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基因ID
- 7852
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UniProt
- P61073
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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