CXCR3 抗体 (AA 1-368) (PE)
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Quick Overview for CXCR3 抗体 (AA 1-368) (PE) (ABIN7979319)
抗原
See all CXCR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-368
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原理
- Anti-CXCR3 Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human CXCR3 shares 86% amino acid (aa) sequence identity with both mouse,rat CXCR3.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CXCR3 recombinant protein (Position: M1-L368). Human CXCR3 shares 86% amino acid (aa) sequence identity with both mouse and rat CXCR3.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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别名
- CXCR3
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背景
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Background: Chemokine receptor CXCR3 is a Galphai protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183. It is mapped to Xq13.1. CXCR3 is expressed on malignant B cells from chronic lymphoproliferative disorders, particularly in patients with CLL, and represents a fully functional receptor involved in chemotaxis of malignant B lymphocytes. It is found that in the absence of known etiologic agents, CXCR3 represents a novel target for therapeutic interference early in type 1 diabetes. CXCR3 signaling is associated with MG pathogenesis and proposed that and CXCR3 may serve as novel drug targets to treat MG. CXCR3A and CXCR3B are involved in the chemotactic and vascular effects of CXCL4L1.
Gene Full Name: C-X-C motif chemokine receptor 3
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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基因ID
- 2833
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UniProt
- P49682
抗原
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