CCL7 抗体 (AA 24-97) (APC)
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Quick Overview for CCL7 抗体 (AA 24-97) (APC) (ABIN7978768)
抗原
See all CCL7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-97
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原理
- Anti-MCP3/CCL7 Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Mouse MCP3 shares 60%,95% amino acid (aa) sequences identity with human,rat MCP3,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
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别名
- CCL7
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背景
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Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.
Gene Full Name: C-C motif chemokine ligand 7
Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.
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基因ID
- 20306
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UniProt
- Q03366
抗原
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