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IL-21 抗体 (AA 65-155)

There are 3+ publications for this product available. The 兔 多克隆 anti-IL-21 antibody is suitable to detect IL-21 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IF (p) 和 IHC (p).
产品编号 ABIN748133
发货至: 中国
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Quick Overview for IL-21 抗体 (AA 65-155) (ABIN748133)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This IL-21 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
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    AA 65-155

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IL-21

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Ma, Sun, Zhai, Yu, Wang, Li, Ding: "Effect of follicular helper T cells on the pathogenesis of asthma." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 967-972, (2017) (PubMed).

    Gong, Zhu, Pang, Ai, Gong, La, Ding: "Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5931-5941, (2017) (PubMed).

    Guan, Wang, Meng, Shi, Jiang, Xiao, Shi, Xu, Zhang: "Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease." in: Cytokine, Vol. 72, Issue 2, pp. 160-5, (2015) (PubMed).

  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL-21

    背景

    Synonyms: Za11, IL-21, CVID11, Interleukin-21, IL21

    Background: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

    基因ID

    59067

    UniProt

    Q9HBE4

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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