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CDC6 抗体 (AA 147-549) (PE)

This 兔 多克隆 antibody specifically detects CDC6 in FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7977954
发货至: 中国
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Quick Overview for CDC6 抗体 (AA 147-549) (PE) (ABIN7977954)

抗原

See all CDC6 抗体
CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

适用

  • 134
  • 28
  • 26
  • 4
  • 1
人, 大鼠

宿主

  • 125
  • 8
  • 1

克隆类型

  • 94
  • 40
多克隆

标记

  • 47
  • 10
  • 8
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CDC6 antibody is conjugated to PE

应用范围

  • 96
  • 41
  • 41
  • 37
  • 30
  • 17
  • 12
  • 10
  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 33
    • 12
    • 11
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-549

    原理

    Anti-Cdc6 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Cdc6 shares 87.3% amino acid (aa) sequence identity with mouse Cdc6.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cdc6 recombinant protein (Position: V147-A549). Human Cdc6 shares 87.3% amino acid (aa) sequence identity with mouse Cdc6.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

    别名

    CDC6

    背景

    Background: Cell division control ptotein 6 homolog, also called CDC18L or CDC6, is a protein that in humans is encoded by the CDC6 gene. By analysis of somatic cell hybrids and by fluorescence in situ hybridization, this gene is mapped to 17q21.2. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. And this protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. This gene is involved in the initiation of DNA replication.

    Gene Full Name: cell division cycle 6

    Sequence Similarities: Belongs to the CDC6/cdc18 family.

    基因ID

    990

    UniProt

    Q99741

    途径

    DNA Replication, Synthesis of DNA
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