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CD1d 抗体 (AA 20-295) (HRP)

The 兔 多克隆 anti-CD1d antibody is suitable to detect CD1d in samples from 人 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7976389
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD1d 抗体 (AA 20-295) (HRP) (ABIN7976389)

抗原

See all CD1d (CD1D) 抗体
CD1d (CD1D) (CD1d Molecule (CD1D))

适用

  • 81
  • 47
  • 25
  • 2
人, 大鼠

宿主

  • 78
  • 31
  • 13
  • 1

克隆类型

  • 79
  • 43
  • 1
多克隆

标记

  • 48
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  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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This CD1d antibody is conjugated to HRP

应用范围

  • 58
  • 41
  • 25
  • 19
  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 12
    • 11
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 20-295

    原理

    Anti-CD1D Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CD1D recombinant protein (Position: E20-W295).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CD1d (CD1D) (CD1d Molecule (CD1D))

    别名

    CD1D

    背景

    Background: CD1D (CD1d molecule) also known as R3G1, Antigen-presenting glycoprotein CD1d, R3G1, CD1D, is the sole group-2 member of the CD1 family of major histocompatibility (MHC)-like glycoproteins. Expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. It is the only member of the group 2 CD1 molecules. CD1d presented lipid antigens activate a special class of T cells, known as Natural Killer T (NKT) cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and IL-4 production. Jayawardena-Wolf et al. described 2 different pathways of Cd1d trafficking to endosomal compartments in mouse cells. A tyrosine-based motif governs recycling between the plasma membrane and the endosome, while Cd1d associates, like major histocompatibility complex class II antigens, with the invariant chain, or II, in the endoplasmic reticulum. Both pathways enhance antigen presentation to Cd1d-restricted natural killer T cells.

    Gene Full Name: CD1d molecule

    基因ID

    912

    UniProt

    P15813

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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