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CD16 抗体 (C-Term) (FITC)

This 兔 多克隆 antibody specifically detects CD16 in FACS. It exhibits reactivity toward 小鼠.
产品编号 ABIN7976223
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for CD16 抗体 (C-Term) (FITC) (ABIN7976223)

抗原

See all CD16 抗体
CD16

适用

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小鼠

宿主

  • 147
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  • 1

克隆类型

  • 193
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  • 1
多克隆

标记

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This CD16 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 19
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    C-Term

    原理

    Anti-CD16/Fcgr3 Antibody FITC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse CD16/Fcgr3, which shares 73.7% amino acid (aa) sequence identity with rat CD16/Fcgr3.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CD16

    别名

    Fcgr3

    背景

    Background: Low affinity immunoglobulin gamma Fc region receptor III-A is a protein that in humans is encoded by the FCGR3A gene. This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: Fc receptor, IgG, low affinity III

    基因ID

    14131

    UniProt

    P08508

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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