CNOT7 抗体 (AA 3-285) (Biotin)
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北京 101111
Quick Overview for CNOT7 抗体 (AA 3-285) (Biotin) (ABIN7976141)
抗原
See all CNOT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-285
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原理
- Anti-CNOT7 Antibody Biotin Conjugated
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CNOT7 recombinant protein (Position: A3-S285).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
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别名
- CNOT7
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背景
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Background: CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene. The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.
Gene Full Name: CCR4-NOT transcription complex subunit 7
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基因ID
- 29883
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UniProt
- Q9UIV1
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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