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Caveolin-1 抗体 (AA 4-178)

The 兔 多克隆 anti-Caveolin-1 antibody (ABIN7975997) specifically detects Caveolin-1 in WB, IHC, IF, FACS 和 IHC (fro). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7975997
发货至: 中国
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Quick Overview for Caveolin-1 抗体 (AA 4-178) (ABIN7975997)

抗原

See all Caveolin-1 (CAV1) 抗体
Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

适用

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人, 大鼠, 小鼠

宿主

  • 162
  • 22
  • 7
  • 1

克隆类型

  • 121
  • 71
多克隆

标记

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This Caveolin-1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

Carrier-free
  • 抗原表位

    • 25
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    AA 4-178

    原理

    Anti-Caveolin-1/CAV1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Caveolin-1 shares 95%,94% amino acid (aa) sequences identity with mouse,rat Caveolin-1,respectively.

    产品特性

    Anti-Caveolin-1/CAV1 Antibody. Tested in Flow Cytometry, IF, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Caveolin-1 recombinant protein (Position: G4-I178). Human Caveolin-1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Caveolin-1, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse Immunohistochemistry (Frozen Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

    别名

    CAV1

    背景

    Background: CAV1 ( Caveolin-1) is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

    Gene Full Name: caveolin 1

    Sequence Similarities: Belongs to the caveolin family.

    分子量

    22 kDa

    基因ID

    857

    UniProt

    Q03135

    途径

    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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