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Cathepsin D 抗体 (AA 201-412) (HRP)

This 兔 多克隆 antibody specifically detects Cathepsin D in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7975839
发货至: 中国
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北京 101111
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Quick Overview for Cathepsin D 抗体 (AA 201-412) (HRP) (ABIN7975839)

抗原

See all Cathepsin D (CTSD) 抗体
Cathepsin D (CTSD)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cathepsin D antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 201-412

    原理

    Anti-Cathepsin D/CTSD Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human Cathepsin D shares 84.4%,84% amino acid (aa) sequence identity with mouse,rat Cathepsin D,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human < a href=https://www.bosterbio.com/anti-cathepsin-d-picoband-trade-antibody-a01361-boster.html>Cathepsin D recombinant protein (Position: M201-L412). Human Cathepsin D shares 84.4% and 84% amino acid (aa) sequence identity with mouse and rat Cathepsin D, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Cathepsin D (CTSD)

    别名

    CTSD

    背景

    Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

    Gene Full Name: cathepsin D

    基因ID

    1509

    UniProt

    P07339

    途径

    Peptide Hormone Metabolism
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