Cathepsin D 抗体 (AA 201-412) (Biotin)
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Quick Overview for Cathepsin D 抗体 (AA 201-412) (Biotin) (ABIN7975833)
抗原
See all Cathepsin D (CTSD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-412
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原理
- Anti-Cathepsin D/CTSD Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human Cathepsin D shares 84.4%,84% amino acid (aa) sequence identity with mouse,rat Cathepsin D,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human < a href=https://www.bosterbio.com/anti-cathepsin-d-picoband-trade-antibody-a01361-boster.html>Cathepsin D recombinant protein (Position: M201-L412). Human Cathepsin D shares 84.4% and 84% amino acid (aa) sequence identity with mouse and rat Cathepsin D, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Cathepsin D (CTSD)
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别名
- CTSD
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背景
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Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.
Gene Full Name: cathepsin D
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基因ID
- 1509
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UniProt
- P07339
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途径
- Peptide Hormone Metabolism
抗原
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