COMT 抗体 (AA 52-271)
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北京 101111
Quick Overview for COMT 抗体 (AA 52-271) (ABIN7975645)
抗原
See all COMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-271
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原理
- Anti-COMT Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human COMT shares 81.9%,81% amino acid (aa) sequence identity with mouse,rat COMT,respectively.
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产品特性
- Anti-COMT Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human COMT recombinant protein (Position: G52-P271). Human COMT shares 81.9% and 81% amino acid (aa) sequence identity with mouse and rat COMT, respectively.
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亚型
- IgG
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anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibody
Verified COMT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (N-Term) antibodyVerified COMT 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) antibodyKO Validated COMT 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibodyCOMT 适用: 人, 大鼠, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibodyCOMT 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS, IF 宿主: 小鼠 Monoclonal 15C10 unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 1-182) antibodyCOMT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4-1A1 unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibodyCOMT 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibodyCOMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibodyCOMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Catechol-O-Methyltransferase (COMT) antibodyKD Validated COMT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3735 unconjugated Recombinant Antibody
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- COMT (Catechol-O-Methyltransferase (COMT))
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别名
- COMT
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背景
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Background: Catechol O-methyltransferase, also called COMT, is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines. This gene is mapped to 22q11.21. Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini.
Gene Full Name: catechol-O-methyltransferase
Sequence Similarities: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family.
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分子量
- 26 kDa
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基因ID
- 1312
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UniProt
- P21964
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途径
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
抗原
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