IL5RA 抗体 (AA 11-110) (Cy3)
Quick Overview for IL5RA 抗体 (AA 11-110) (Cy3) (ABIN747836)
抗原
See all IL5RA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-110
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Cow,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human IL-5R alpha
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
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别名
- IL5RA/CD125
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背景
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Synonyms: Interleukin-5 receptor alpha, CD125 antigen, CDw125, HSIL5R3, IL5R, IL-5R, Interleukin 5 Receptor alpha, Interleukin 5 receptor subunit alpha, interleukin 5 receptor type 3, MGC26560, IL5RA, IL-5R alpha, IL5RA_HUMAN.
Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
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基因ID
- 3568
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UniProt
- Q01344
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途径
- JAK/STAT Signaling
抗原
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