我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

CBL 抗体 (AA 556-906)

Name: CBL 抗体 (AA 556-906)
SKU: ABIN7975084
Availability: OutOfStock

The 兔多克隆 anti-CBL antibody is suitable to detect CBL in samples from 人, 小鼠和大鼠. It has been validated for WB, IHC, IF, FACS 和 ICC.

产品编号 ABIN7975084

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CBL 抗体 (AA 556-906) (ABIN7975084)

抗原

See all CBL 抗体

CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CBL antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

质量等级

Carrier-free

Discover our top product CBL Primary Antibody

抗原表位
34

27

20

18

17

13

11

5

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 556-906

原理

Anti-CBL Antibody

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

Human CBL shares 84% amino acid (aa) sequence identity with mouse CBL.

产品特性

Anti-CBL Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CBL recombinant protein (Position: A556-T906). Human CBL shares 84% amino acid (aa) sequence identity with mouse CBL.

亚型

IgG
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3B12 unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 736-835) antibody
CBL 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 6D12 unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibody
CBL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (Internal Region) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibody
CBL 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr674) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 548-847) antibody
CBL 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr700) antibody
CBL 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody
CBL 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr774) antibody
KD Validated CBL 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB7555 unconjugated Recombinant Antibody

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

别名

CBL

背景

Background: CBL (Cbl proto-oncogene) is also known as C-CBL, RNF55, CBL2 and E3 ubiquitin protein ligase. CBL is mapped to chromosome 11q23.3-qter by molecular characterization of the breakpoints in 2 somatic cell hybrids. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder.
Gene Full Name: Cbl proto-oncogene
Sequence Similarities: Contains 1 Cbl-PTB (Cbl-type phosphotyrosine-binding) domain.

分子量

120 kDa

基因ID

867

UniProt

P22681

途径

TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals