TNNI3 抗体 (C-Term) (Cy3)
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Quick Overview for TNNI3 抗体 (C-Term) (Cy3) (ABIN7974976)
抗原
See all TNNI3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Cardiac Troponin I/TNNI3 Antibody Cy3 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cardiac Troponin I/TNNI3, which shares 95.5% amino acid (aa) sequence identity with mouse and rat TNNI3.
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亚型
- IgG
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anti-Cardiac Troponin I (TNNI3) (AA 102-210) antibody
TNNI3 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 2-211) antibodyTNNI3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-211) antibodyTNNI3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 1-211) antibodyTNNI3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (AA 117-127) antibodyVerified TNNI3 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) (pSer44) antibodyTNNI3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 2I-14 unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 8I-7 unconjugated
anti-Cardiac Troponin I (TNNI3) antibodyTNNI3 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 8I-7 unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- TNNI3 (Cardiac Troponin I (TNNI3))
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别名
- TNNI3
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背景
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Background: Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19.
Gene Full Name: troponin I3, cardiac type
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基因ID
- 7137
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UniProt
- P19429
抗原
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